Publications from 2009

First author from Finsen Laboratory

Alpízar-Alpízar, W., Laerum, O.D., Illemann, M., Ramírez, J.A., Arias, A., Malespín-Bendaña, W., Ramírez, V., Lund, L.R., Borregaard, N., Nielsen, B.S.:
Neutrophil gelatinase-associated lipocalin (NGAL/Lcn2) is upregulated in gastric mucosa infected with Helicobacter pylori.
Virchows Arch. 455:225–233.

Illemann, M., Bird, N., Majeed, A., Lærum, O.D., Lund, L.R., Danø, K. and Nielsen, B.S.:
Two Distinct Expession Patterns of Urokinase, Urokinase Receptor and Plasminogen Activator Inhibitor-1 in Colon Cancer Liver Metastases.
International Journal of Cancer. 124: 1860-1870.

Almasi, C.E., Høyer-Hansen, G., Christensen, I.J. and Pappot, H.:
Prognostic significance of urokinase plasminogen activator receptor and its cleaved forms in blood from patients with non-small cell lung cancer.
APMIS. 117: 755-61.

Engelholm, L.H., Ingvarsen, S., Jürgensen, H.J., Hillig, T., Madsen, D.H., Nielsen, B.S. and Behrendt, N.:
The collagen receptor uPARAP/Endo180.
Frontiers in Bioscience, 14: 2103-14.

Juncker-Jensen, A., Rømer, J., Pennington, C.J., Lund, L.R., and Almholt, K.:
Spontaneous metastasis in matrix metalloproteinase 3-deficient mice.
Mol. Carcinogenesis. 48: 618–625.


Joint publications with co-author from Finsen Laboratory

Doehn, U., Hauge, C., Frank, S.R., Jensen, C.J., Duda, K., Nielsen, J.V., Cohen, M.S., Johansen, J.V., Winther, B.R., Lund, L.R., Winther, O., Taunton, J., Hansen, S.H. and Frödin, M.:
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.
Mol Cell. 35:511-22.

Rowe, R.G., Li, X.Y., Hu, Y., Saunders, T.L., Virtanen, I., Garcia de Herreros, A., Becker, K.F., Ingvarsen, S., Engelholm, L.H., Bommer, G.T., Fearon, E.R. and Weiss, S.J.:
Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs.
J Cell Biol. 184:399-408.

Szabova L, Yamada SS, Wimer H, Chrysovergis K, Ingvarsen S, Behrendt N, Engelholm LH, Holmbeck K.:
MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.
J Bone Miner Res. 24:1905-16.

Axelsen, T.V., Holm, A., Birkelund, S., Christiansen, G., Ploug, M. and Holm, I.E.:
Specific recognition of the C-terminal end of Abeta946;42 by a high affinity monoclonal antibody.
Mol. Immunol. 46: 2267-73.

Pragner, G. W., Mihaly, J., Brunner, P.M., Koschelnick, Y., Høyer-Hansen, G. and Binder, B.:
Urokinase (uPA) mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein (XIAP).
Blood. 113:1383-90.

Blouse, G.E., Dupont, D.M., Schar, C.R., Jensen, J.K., Minor, K.H., Anagli, J.Y., Gårdsvoll, H., Ploug, M., Peterson, C.B., and Andreasen, P.A.:
Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extended binding surface and induce mutual conformational rearrangements.
Biochemistry. 48, 1723-1735.

Lomholt, A.F., Høyer-Hansen, G., Nielsen, H.J. and Christensen, I.J.:
Intact and cleaved forms of the urokinase receptor enhance discrimination of cancer from non-malignant conditions in patients presenting with symptoms related to colorectal cancer.
Br J Cancer. 101: 992-7.

Klintman , M., Ornbjerg, W.S., Christensen, I.J., Bræmer, H.P., Fernö, M., Malmberg, M., Mouridsen, H., Cold, F., Schrohl, A.S., Foekens, J.A., Malmström, P. and Brünner, N.:
Association between tumor tissue TIMP-1 levels and objective response to first-line chemotherapy in metastatic breast cancer.
Breast Cancer Res Treat. Epub ahead of print

Jensen, T.O., Schmidt, H., Møller, H.J., Høyer, M., Maniecki, M.B., Sjoegren, P., Christensen, I.J. and Steiniche, T.:
Macrophage markers in serum and tumor have prognostic impact in American Joint Committee on Cancer stage I/II melanoma.
J Clin Oncol. 27: 3330-7.

Marquard, L., Poulsen, C.B., Gjerdrum, L.M., de Nully Brown, P., Christensen, I.J., Jensen, P.B., Sehested, M., Johansen, P. and Ralfkiaer, E.:
Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas.
Histopathology. 54: 688-98.

Frederiksen, C., Lomholt, A.F., Davis, G.J., Dowell, B.L., Blankenstein, M.A., Christensen, I.J., Brünner, N. and Nielsen, H.J.:
Changes in plasma TIMP-1 levels after resection for primary colorectal cancer.
Anticancer Res. 29: 75-81.

Larsen, J.M., Christensen, I.J., Nielsen, H.J., Hansen, U., Bjerregaard, B., Talts, J.F. and Larsson, L.I.:
Syncytin immunoreactivity in colorectal cancer: potential prognostic impact.
Cancer Lett. 280: 44-9.

Petri, A.L., Kjaer, S.K., Christensen, I.J., Blaakaer, J., Hogdall, E., Jeppesen, U., Mosgaard, B.J., Pagel, J.D., Stilling, L., Thranov, I. and Hogdall, C.:
Validation of epithelial ovarian cancer and fallopian tube cancer and ovarian borderline tumor data in the Danish Gynecological Cancer Database.
Acta Obstet Gynecol Scand. 88: 536-42.

Begum, F.D., Høgdall, E., Kjaer, S.K., Blaakaer, J., Christensen, I.J., Christensen, L. and Høgdall, C.:
Preoperative serum tetranectin, CA125 and menopausal status used as single markers in screening and in a risk assessment index (RAI) in discriminating between benign and malignant ovarian tumors.
Gynecol Oncol. 113: 221-7.

Høgdall, E.V., Ringsholt, M., Høgdall, C.K., Christensen, I.J., Johansen, J.S., Kjaer, S.K., Blaakaer, J., Ostenfeld-Møller, L., Price, P.A. and Christensen, L.H.:
YKL-40 tissue expression and plasma levels in patients with ovarian cancer.
BMC Cancer. 9: 8.

Henic, E., Noskova, V., Høyer-Hansen, G., Hansson, S. and Casslén, B.: Estradiol attenuates EGFnduced rapid uPAR mobilization and cell migration via the G-protein-coupled receptor 30 in ovarian cancer cells.-i
Int J Gynecol Cancer. 19:214-22.