Publications from 2007

Jacobsen, B., Gårdsvoll, H., Funch, G.J., Østergaard, S., Barkholt, V. & Ploug, M.:
One-step affinity purification of recombinant urokinase-type plasminogen activator receptor using a synthetic peptide developed by combinatorial chemistry.
Protein Expression and Purification, 2007, 52: 286-296.

Nielsen, B.S., Rank, F., Illemann, M., Lund, L.R. & Danø, K.:
Stromal cells associated with early invasive foci in human mammary ductal carcinoma in situ co-express urokinase and urokinase receptor.
Int. J. Cancer, 2007, 120: 2086-2095.

Høyer-Hansen, G. & Lund, I.K.:
Urokinase receptor variants in tissue and body fluids.
Adv. Clin. Chem.. 2007, 44: 65-102.

Ostrowski, S.R., Shulman, C.E., Peshu, N., Staalsoe, T., Høyer-Hansen, G., Pedersen, B.K., Marsh, K. And Ullum, H.:
Elevated plasma urokinase receptor predicts low birth weight in maternal malaria.
Parasite Immunology. 2007, 29: 37-46.

Wahlberg, P, Bodén, I., Paulsson, J., Lund, L.R., Liu, K. & Ny,T,:
Functional corpora lutea are formed in MMP inhibitor-treated plasminogen deficient mice.
Endocrinology. 2007, 148: 1226-1234.

Almholt, K., Green, K.A., Juncker-Jensen, A., Nielsen, B.S., Lund, L.R. & Rømer, J.:
Extracellular proteolysis in transgenic mouse models of breat cancer.
J. Mammary Gland Biol. Neoplasia. 2007, 12: 83-97.

Gårdsvoll, H., Hansen, L. V., Jørgensen, T.J.D., Danø, K. and Ploug, M.:
A new tagging system for production of recombinant proteins in Drosophila S2 cells, using the third domain of the urokinase receptor.
Protein Purification and Expression, 2007, 52: 384-394.

Gårdsvoll, H. & Ploug, M.:
Mapping of the vitronectin binding site on the urokinase receptor. Involvement of a composite interface of domain I and the flanking interdomain linker region.
J. Biol. Chem., 2007, 282: 13561-13572.

Pass, J., Jögi, A., Lund, I.K., Rasch, M.G., Gårdsvoll, H., Lund, L.R., Ploug, M., Rømer, J., Danø, K. & Høyer-Hansen, G.:
Murine monoclomal antibodies against murine uPA receptor produced in gene-deficient mice: Inhibitory effects on lingand binding.
Thromb.Haemost. 2007, 97: 1013-1022.

Jögi A., Pass J., Høyer-Hansen G., Lund L. R., Nielsen B. S., Danø K., and Rømer J.:
Systemic administration of anti-urokinase plasminogen activator receptor monoclonal antibodies induces hepatic fibrin deposition in tissue-type plasminogen activator deficient mice.
J Thromb Haemost. 2007, 5:1936-1944.

Sulek, J., Shireman, J., Molinolo, A., Madsen, D.H., Engelholm, L.H., Behrendt, N., Wagenaar-Miller, R. and Bugge, T.H.:
Expression of the collagen internalization receptor uPARAP/Endo180 in stroma of oral squamous cell carcinoma.
J. Histochem.Cytochem. 2007, 55: 347-353.

Kjaergaard, M., Gårdsvoll, H., Hirschberg, D., Nielbo, S., Mayasundari, A., Peterson, C., Jansson, A., Jørgensen, T.J.D., Poulsen, F. M., and Ploug, M.:
Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris.
Protein Science. 2007, 16: 1934-1945.

Petri, A.L., Høgdall, E., Engelholm, S.A., Christensen, I.J., Kjaer, S.K.& Høgdall, C.K.:
[Identification of new ovarian cancer biomarkers with proteomic analyses--the diagnostic tool of the future?].
Ugeskr Laeger. 2007, 169: 2614-9.

Johansen, J.S., Brasso, K., Iversen, P., Teisner, B., Garnero, P., Price, P.A. & Christensen, I.J.:
Changes of biochemical markers of bone turnover and YKL-40 following hormonal treatment for metastatic prostate cancer are related to survival.
Clin Cancer Res. 2007, 13: 3244-9.

Hansen, L.V., Skov, B.G., Ploug, M & Pappot H.:
Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer.
Lung. Cancer. 2007, 58: 260-266.

Madsen, D.H., Engelholm, L.H., Ingvarsen, S., Hillig, T., Wagenaar-Miller, R.A., Kjøller, L., Gårdsvoll, H., Høyer-Hansen, G., Holmbeck, K., Bugge, T.H., Behrendt, N.:
Extracellular collagenases and the endocytic receptor, uPARAP/Endo180, cooperate in fibroblast-mediated collagen degradation.
J. Biol. Chem. 2007, 282:27037-27045.

Wagenaar-Miller, R.A., Engelholm, L.H., Kuhnen, M., Kahan, S., Yamada, S., Nielsen, B.S., Behrendt, N., Bugge, T.H. and Holmbeck, K.:
Complementary roles of intracellular and pericellular collagen degradation pathways in vivo.
Moll.Cell. Biol. 2007, 27: 6309-22

Heissig, B., Lund, L.R., Akiyama, H., Ohki, M, Morita, Y., Rømer, J., Nakauchi, H., Okumura, K., Ogawa, H., Werb, Z., Danø, K., and Hattori, K.:
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
Cell Stem Cell. 2007, 1:658-670.

Nordentoft, T., Rømer, J. and Sørensen, M.:
Sealing of Gastrointestinal Anastomoses with a Fibrin Glue-Coated Collagen Patch: A Safety Study.
J. of Investigative Surgery. 2007, 20:363 – 369.