Ploug Group

Key publications

Hansen, L.V., Lærum, O.D., Illemann, M., Nielsen, B.S., and Ploug, M.:
"Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma
Int. J. Cancer, 2008, 122: 734-741

Hansen, L.V., Skov, B. G., Ploug, M., and Pappot, H.:
"Tumor cell Expression of C4.4A, a structural homologue of the urokinase receptor, is correlated with poor prognosis in non-small cell lung cancer."
Lung Cancer, 2007, 58: 260-266
Llinas, P., Le Du, M., Gårdsvoll, H., Danø, K., Ploug, M., Gilquin, B., Stura,

Gårdsvoll, H and Ploug, M.:
"Mapping of the vitronectin binding site on the urokinase receptor. Involvement of a coherent receptor interface comprising residues from both domain I and the flanking interdomain linker region."
J. Biol. Chem., 2007, 282: 13561-13572

Gårdsvoll, H., Gilquin, B., LeDu, M.H., Ménez, A., Jørgensen, T.D.J. and Ploug, M.:
"Charaterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical crosslinking."
J. Biol. Chem., 2006, 281: 19260-19272

E.A., and Ménez, A .:
"Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide."
EMBO J., 2005, 24: 1655-1663