Signe Ingvarsen - Recent Publications

Szabova L, Yamada SS, Wimer H, Chrysovergis K, Ingvarsen S, Behrendt N, Engelholm LH, Holmbeck K.:
MT1-MMP and type II collagen specify skeletal stem cells and their bone and cartilage progeny.
J Bone Miner Res. 2009;24:1905-16.

Rowe RG, Li XY, Hu Y, Saunders TL, Virtanen I, Garcia de Herreros A, Becker KF, Ingvarsen S, Engelholm LH, Bommer GT, Fearon ER, Weiss SJ.:
"Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs."
J Cell Biol. 2009, 184:399-408.

Engelholm, L.H., Ingvarsen, S., Jürgensen, H.J., Hillig, T., Madsen, D.H., Nielsen, B.S. and Behrendt, N.:
"The collagen receptor uPARAP/Endo180."
Frontiers in Bioscience, 2009. 14:2103-14.

Hillig, T., Engelholm, L.H., Ingvarsen, S., Madsen, D.H., Gårdsvoll, H., Larsen, J.K., Ploug, M., Danø, K., Kjøller, L. and Behrendt, N.: (2008).
"A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor."
J Biol Chem. 2008, 283: 15217-15223.

Ingvarsen, S., Madsen, D.H., Hillig, T., Lund, L.R., Holmbeck, K., Behrendt, N. and Engelholm, L.H.:
"Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72 kDa gelatinase, MMP-2, on fibroblasts and fibrosarcoma cells."
Biological Chemistry. 2008, 398: 943-953.

Madsen, D.H., Engelholm, L.H., Ingvarsen, S., Hillig, T., Wagenaar-Miller, R.A., Kjøller, L., Gårdsvoll, H., Høyer-Hansen, G., Holmbeck, K., Bugge, T.H. and Behrendt, N.:
"Extracellular collagenases and the endocytic receptor, uPARAP/Endo180, cooperate in fibroblast-mediated collagen degradation."
J. Biol. Chem. 2007. 282: 27037-27045.