Gunilla Høyer-Hansen - Key publications

Almasi, C.E., Brasso K., Iversen, P., Pappot, H., Høyer-Hansen, G., Danø, K. and Christensen, I.J.:
Prognostic and predictive value of intact and cleaved forms of the urokinase plasminogen activator receptor in metastatic prostate cancer.
Prostate, 2010; Epub ahead of print.

Thurison, T., Lomholt, A.F., Rasch, M.G., Lund, I.K., Nielsen, H.J., Christensen, I.J. and Høyer-Hansen, G.:
A new assay for the measurement of the liberated domain I of the urokinase receptor in plasma improves the prediction of survival in colorectal cancer.
Clin. Chem. 2010; 56:1636-40.

Jögi, A., Rønø, B., Lund, I.K., Nielsen B.S., Ploug, M., Høyer-Hansen, G,, Rømer, J. and Lund, L.R.:
Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice.
PLoS One., 2010; 5:e12746

Lund, I.K., Jögi, A., Rønø, B., Rasch, M.G., Lund, L.R., Almholt, K., Gårdsvoll, H., Behrendt, N., Rømer, J.R.Høyer-Hansen, G.:
Antibody-mediated targeting of the uPA proteolytic function neutralizes fibrinolysis in vivo.
J Biol Chem. 2008, 283: 32506-15.

Henic, E., Borgfeldt, C., Christensen, I.J., Casslén, B., Høyer-Hansen, G.:
"Cleaved forms of the urokinase plasminogen activator receptor in plasma enhance discrimination of benign from malignant disease and predict survival in patients with ovarian cancer."
Clin Cancer Res., 2008, 14: 5785-5793.

Pass, J., Jögi, A., Lund,I.K., Rønø, B., Rasch,M.G., Gårdsvoll,H., Lund, L.R., Ploug, M., Rømer, J., Danø, K. and Høyer-Hansen, G.:
"Murine monoclonal antibodies against murine uPA receptor produced in gene-deficient mice: Inhibitory effects on receptor-mediated uPA activity in vitro and in vivo."
Thromb.Haem., 2007, 97: 1013-1022.

Piironen, T., Haese, A., Huland, H., Steuber, T., Christensen, I.J., Brünner, N., Danø, K., Høyer-Hansen, G. and Lilja, H.:
"Enhanced discrimination of benign from malignant prostatic disease by novel selective measurements of cleaved forms of urokinase receptor in serum."
Clin.Chem., 2006, 52: 838-844.

Piironen T, Laursen B, Pass J, List K, Gårdsvoll H, Ploug M, Danø K and Høyer-Hansen G.:
"Specific immunoassays for the detection of intact and cleaved forms of the urokinase receptor."
Clin. Chem., 2004, 50: 2059-2068.

Høyer-Hansen, G., Pessara, U., Holm,A., Pass, J., Weidle, U., Danø, K. & Behrendt, N.:
"Urokinase-catalysed cleavage of the urokinase receptor requires an intact glycolipid anchor."
Biochem.J., 2001, 358: 673-679.