Benedikte Jacobsen - Publications

B. Jacobsen:
Expression and prognostic significance of C4.4A in non-small cell lung cancer.
PhD thesis, University of Copenhagen, 2011.

B. Jacobsen, E. Santoni-Rugiu, M. Illemann, M.C. Kriegbaum, O.D. Lærum, and M. Ploug.
Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma.
International Journal of Cancer, 2011, in press.

M.C. Kriegbaum, M. Persson, L. Haldager, W. Alpízar-Alpízar, B. Jacobsen, H. Gårdsvoll, A. Kjær, and M. Ploug:
Rational targeting of the urokinase receptor (uPAR): Development of inhibitors and nonnvasive imaging probes-i.
Current Drug Targets, 2011, in press.

H. Gårdsvoll, B. Jacobsen, M.C. Kriegbaum, N. Behrendt, L. Engelholm, S. Østergaard, and M. Ploug:
Conformational regulation of urokinase receptor (uPAR) function. Impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.
Journal of Biological Chemistry, 2011, 23: 33544-33556.

M.C. Kriegbaum, B. Jacobsen, A. Hald, and M. Ploug.
Expression of C4.4A, a structural homolog of uPAR, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis.
Journal of Histochemistry and Cytochemistry, 2011, 59: 188-201.

Jacobsen, B. and Ploug, M.:
"The urokinase receptor and its structural homologue C4.4A in human cancer: Expression, prognosis and pharmacological inhibition."
Current Medicinal Chemistry, 2008, 15: 2559-73..

M. Kjaergaard, L.V. Hansen, B. Jacobsen, H. Gårdsvoll and M. Ploug.:
"Structure and ligand interactions of the urokinase-type plasminogen activator receptor (uPAR)."
Frontiers in Biosciences, 2008, 13: 5441-5461.

B. Jacobsen, M. Kjaergaard, H. Gårdsvoll and M. Ploug.:
"Structure and inhibition of the urokinase-type plasminogen activator receptor (uPAR)."
The Cancer Degradome-Proteases and Cancer Biology, D. Edwards, G. Høyer-Hansen, F. Blasi and B.F. Sloane (eds),
Springer Verlag, 2007.

B. Jacobsen, H. Gårdsvoll, G. Juhl Funch, S. Østergaard, V. Barkholt and M. Ploug.:
"One-step affinity purification of recombinant urokinase-type plasminogen activator receptor using a synthetic peptide developed by combinatorial chemistry."
Protein Expression and Purification, 2007, 52: 286-296.

B. Jacobsen:
"Purification and photoaffinity labeling of uPAR with synthetic peptide antagonists."
Master thesis, Danmarks Tekniske Universitet, 2006, 1-68.